Health EU management is looking with strong conviction into a bright future of a European mission on creating the first European Integrative Human Avatar Platform under the umbrella of Digital Healthcare enabled by Artificial Intelligence and Internet of Things.Today, we launch the Health EU Manifesto to unify all forces in medicine, biology, social sciences and engineering Europe under the visionary concept of Human Avatars for personalized, preventive and participatory healthcare. We invite all interested universities, research institutes, hospitals, industries and citizen/patient associations and other stakeholders to sign our Manifesto as an expression of direct support!